$ads={1}
Principle Roles & Responsibilities / Accountabilities
Drive discovery and translational research aimed at identifying, characterizing, and interpreting results for novel oncology and immune oncology therapeutics with cross-functional input.
Design, develop, execute, and troubleshoot assays for target validation, lead candidate selection and characterization and mechanism of action studies to support therapeutic pipeline programs
Effectively present and communicate research findings to internal teams and external scientific community and partners
Prepare reports, publications, presentations, regulatory documents and SOPs.
Manage contract research organization relationships to ensure progress on projects
Investigate and develop methods or technologies for the rapid advancement of projects. Stay up to date with relevant technical and intellectual scientific expertise in tumor biology, immuno-oncology, pharmacology and cancer modelling.
Other related duties as required, including but not limiting to organizing and maintaining laboratory and training associates and/or junior scientists.
Work in a flexible schedule to meet deadlines.
Qualification and Experience
Education/Qualifications
Ph.D. or M.S. in cancer biology, molecular biology, immunology or a related field. PhD with medical knowledge (MD) is a plus. Post-doctoral training experience is preferred. Industrial experience in drug discovery is a plus. Oversea education and/or training experience is preferred.
Leadership Competencies
Should communicate effectively, collaborate efficiently with co-workers (cross functions and/or sites), and be able to train junior level associates and/or scientists.
Job Required Competencies
Deep knowledge of cancer biology or immune-oncology is required.
A proven track record of high productivity and scientific publications in peer reviewed journals
Knowledge and experience in key areas of tumor biology including, but not limited to, oncogenic signaling, tumor microenvironment, metabolism, tumor immunology and epigenetic deregulation is preferred.
Should be proficient in designing and conducting experiments involving the state of the art techniques within the areas of cancer biology, immunology, biochemistry, molecular biology, and pharmacology. Experience in genetics/genomics e.g., CRISPR/Cas9 genome editing is a plus.
Experience delivering in vivo pharmacology studies in mouse tumor models, including dose-finding tolerability studies, PK/PD and efficacy studies, strongly encouraged.
Experience developing and working with complex in vivo models such as xenograft, patient derived xenograft (PDX), syngeneic and autochthonous mouse models is a plus.
Good communication in English and be capable of presenting results both inside and outside of company. Be able to record and present results in English, fluent Chinese is a plus.
Strong interpersonal and collaboration skills together with motivation, attention to detail, ability to think independently and fully integrate into a high achieving team-oriented environment
Have and maintain thorough knowledge of related scientific field and apply this knowledge to advance projects or programs.
Title of positions (Principal Associate, Scientist, Senior Scientist, or Principal Scientist) matched with candidate’s qualifications and years of experience.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Roche is an Equal Opportunity Employer.
